REAL Madrid are looking to build on their success after victory last time out against struggling Eibar.
But despite goals from Toni Kroos, Sergio Ramos and Marcelo, Zinedine Zidane was furious with his stars who failed to impress him in the 3-1 win.
Valencia sit at seventh in the league, however they are only four points away from securing a Champions League qualification place.
The visitors cannot afford to see any points lost against Los Blancos considering their 1-1 draw against Levante last week.
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Zidane will have to be without Mariano Diaz, Luka Jovic and Nacho as they all remained unavailable through injury.
Lucas Vasquez and Gareth Bale also remain a doubt for Real Madrid.
Valencia are still without Christiano Piccini, and centre-back duo Ezequiel Garay and Gabrial Paulista as they are recovering from injury at the sidelines.
Hazard has had a tricky run with a stop-start season with Real, however his assist against Eibar last weekend suggests he's ready to get back on form.
Valencia's Coquelin seems to be Valencia's most competent midfielder and will be needed if Valencia want to beat Real and get closer to that CL qualification place.
*All odds from Ladbrokes and correct at time of publication.