Great Britain

Kids given paracetamol in first 2 years of their life are ‘more at risk developing asthma by 18’

ASTHMA DRUG LINK

Research found that the chance of developing the lung condition if people had a particular genetic make-up

KIDS given paracetamol in their first two years of life may be at a higher risk of developing asthma by 18, a study has found.

The chance is greater if they have a particular genetic make-up.

 Research found that the chance of developing asthma by 18 is greater if people had a particular genetic make-up

Alamy

Research found that the chance of developing asthma by 18 is greater if people had a particular genetic make-up

The research looked at 620 children who had been followed from birth to 18, all of whom had a relative with an allergic disease.

After their birth, a research nurse rang the family every four weeks for the first 15 months, and then at 18 months and at two-years-old to ask how many days in the previous weeks had the child taken paracetamol.

But the authors of the Australian study said the findings showed a link between paracetamol and asthma, not that the drug caused the lung condition.

Researchers found one variant of the GSTP1 gene - GSTP1 Ile/Ile was associated with almost twice the risk of developing asthma.

Xin Dai, a nurse and PhD student at the university, said: “We found that children with the GSTP1 Ile/Ile variant had 1.8 times higher risk of developing asthma by the age of 18 years for each doubling of the days of paracetamol exposure when compared to children who were less exposed.

“In contrast, increasing paracetamol exposure in children who had other types of GSTP1 did not alter the risk of asthma.

“We also found effects in children who had a variant of GSTM1 in which one part is not functioning. In these children increasing paracetamol use was associated with small, but significant reduction in the amount of air they could forcibly breathe out in one second at 18 years."Paracetamol is recommended by the NHS to treat most kinds of childhood ailments."

Mum's agony over daughter, 5, who died of asthma attack after GP turned her away for 'being 10 minutes late'

Football news:

Smart ticket sales in Poland: roommates sit next to each other, social stations are created automatically, and attendance increases by 20%
A gay player from the Premier League wrote an anonymous letter published in The Sun: I hope that one day I will be able to confess. I feel trapped
Zinedine Zidane: what Courtois does in every game is phenomenal
Tottenham fans will launch a plane with a Levi banner-on the way out at the game with Arsenal
Zinedine Zidane: I would like VAR not to be used
Tottenham – Arsenal. Who will win: Mourinho or Arteta?
Zinedine Zidane: if the referee gives a penalty, it means it is a penalty