Three children and a woman are fighting for their lives, and another badly injured after a car they were travelling in smashed into a tree in the early hours of this morning.
An ambulance which was taking a patient to hospital came across the crash site at 4.45am.
Five more ambulances dashed to the scene in the Bordesley Green area of Birmingham.
Four children and a woman were found inside the wrecked silver Ford Fiesta which had collided with a tree.
Three children are said to be in a serious condition, while one has a fractured collarbone.
A 48-year-old resident living near to the crash site said she was awoken by a ‘lone constant scream.’
She told Birmingham Live: "We heard a scream. It was constant like a horror scream. I could tell it was a lady. "It was awful as at that time the road is quiet.
"Neighbours were looking out. I looked outside and there were about four ambulances and six to seven police cars.
"My neighbour said there’d been an accident with children involved."
Police remain at the scene, with the road blocked off in both directions, while an investigation is ongoing.
West Midlands Police spokeswoman said: "We are investigating after a car hit a tree on Belchers Lane, Bordesley Green at 4.45am today.
"A woman and three children have been taken to hospital where their injuries are described as serious.
"A fourth child has also been taken to hospital with a fractured collar bone.
"Belchers Lane at the junction of Cotterills Lane is likely to remain closed for most of the morning.
"Investigations are ongoing and anyone with information can contact us via Live Chat on our website or call 101. "