"We are very encouraged that our first target of exhausting the first batch of 80,000 vaccines from Johnson & Johnson in two weeks has been achieved and exceeded. We have taken every opportunity to learn from this process and continue to refine the programme in preparation for rollout to the larger community in the subsequent phases," he said in a statement.
The first batch of 80,000 vaccines arrived in SA in mid-February, with the second batch having arrived at the weekend.
Mkhize also reported on Wednesday night that there were now 1,516,262 confirmed cases of Covid-19 recorded across SA after 1,447 new infections were identified since Tuesday.
The new cases come from 33,498 tests, at a positivity rate of 4.3%.
Mkhize also confirmed that 95 new Covid-19 related deaths were reported in the past 24 hours. Of these, 30 were in Gauteng, 25 were in the Western Cape, 19 were in the Free State, eight were in KwaZulu-Natal, seven were in Mpumalanga, five were in the Eastern Cape and one was in the Northern Cape. There were no new deaths recorded in Limpopo or North West.
To date, 50,366 Covid-19 related fatalities have been confirmed across SA.
Mkhize said 1,434,772 recoveries had been recorded, at a recovery rate of 94.6%.